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Science

Notta, F., Chan-Seng-Yue, M., Lemire, M. et al. (2016) A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns, Nature 538: 378–382 doi:10.1038/nature19823

Nature

Chen, G., Bradford, W.D., Seidel, C.W. and Li, R. (2012) Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy, Nature 482: 246–250 doi:10.1038/nature10795

Nature

Potapova, T. A., Zhu, J. and Li, R. (2013). Aneuploidy and chromosomal instability: a vicious cycle driving cellular evolution and cancer genome chaos, Cancer Metastasis Reviews 32: 377–389 doi:10.1007/s10555–013–9436–6

Cancer Metastasis Reviews

Chen, G., Rubinstein, B. and Li, R. (2012). Whole chromosome aneuploidy: big mutations drive adaptation by phenotypic leap, BioEssays 34: 893–900 doi:10.1002/bies.201200069

BioEssays

Baker, D., Jeganathan, K., Cameron, J. et al. (2004) BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice, Nat Genet 36: 744–749 doi:10.1038/ng1382

Nat Genet

Baker, D.J., Dawlaty, M.M., Wijshake, T. et al. (2013) Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan, Nature Cell Biology 15: 96–102 doi:10.1038/ncb2643

Nature Cell Biology

Sackton, K., Dimova, N., Zeng, X. et al. (2014) Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C, Nature 514: 646–649 doi:10.1038/nature13660

Nature

Martincorena, I. and Campbell, P.J. (2015) Somatic mutation in cancer and normal cells, Science 349: 1483–1489 doi:10.1126/science.aab4082

Science

Stephens, P. J., Greenman, C. D., Fu, B. et al. (2011) Massive genomic rearrangement acquired in a single catastrophic event during cancer development, Cell 144: 27–40 doi:10.1016/j.cell.2010.11.055

Cell

Wu, S., Turner, K.M., Nguyen, N. et al. (2019) Circular ecDNA promotes accessible chromatin and high oncogene expression, Nature 575: 699–703 doi:10.1038/ s41586–019–1763–5